(B) The term "enzyme" was first coined and used by the German physiologist Wilhelm $K\ddot{u}hne$ in $1877$.He used this term to describe the biologic

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(B) The term "enzyme" was first coined and used by the German physiologist Wilhelm $K\ddot{u}hne$ in $1877$.He used this term to describe the biological catalysts that were previously referred to as "ferments" in the context of fermentation processes.Therefore, the correct option is $B$.